Assuming you are looking for the official PSP games in Spanish (Español) and using a modern emulator (like PPSSPP) or a modded PSP/Vita, here is the useful information you need regarding ISO and PKG formats.
If you see files labeled "Ascension" for the PSP, they are usually modded versions god of war ascension psp iso espa%C3%B1ol pkg
God of War: Ghost of Sparta is one of the most demanding PSP games. If you experience stuttering: Assuming you are looking for the official PSP
: The game can be played on PC using the RPCS3 emulator, though it requires a powerful CPU to run smoothly. god of war ascension psp iso espa%C3%B1ol pkg